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Heavy metals known to be accumulated in plants adversely affect human health. The present study aims to control the heavy metal pollution in soil and to enhance the plant growth by compost and Trichoderma harzianum. Sehar variety of wheat was selected for this study. Experiment was organized in completely randomized design in different sets i.e., 1^st set received only inoculum of T. harzianum (TH), 2^nd set of treatment received 10 ppm of Mg and Zn alone, 3^rd set received Zn/Mg + compost + TH and 4^th set was incurred by C + TH. While, control treatment contained compost only. The experiment was conducted in growth room at 25°C with 16h photoperiod. Results revealed that metal alone (Mg and Zn) showed the drastic effect on plant growth. Both the metals significantly inhibit the growth of wheat plant. While, the polygonal interaction of compost-metal-fungi-plant showed significant increase in plant shoot, root length and biomass as compared to other treatments. The growth trend was found as:  Compost + Zn/ Mg + TH > Compost + TH >  Compost + Zn + Mg >  Compost + Zn/ Mg. The result revealed that both the bio-control (Compost and TH) could be used to control the heavy metal pollution in soil.