This research work envisages photocatalytic degradation of pharmaceutical wastewater of a well-known pharmaceutical multinational industry located in Karachi. The oxidizing agents TiO₂ (anatase), ZnO₂ and H₂O₂ were used along with UV radiations. The temperature maintained at 38C and pH was 9 and 4 in a stirrer bath reactor equipped with 8 UV tubes. These catalysts were found to be very effective in degradation of pharmaceutical wastewater. The synergistic effect of TiO₂ with H₂O₂ gave the best results i.e 45.11% degradation in comparison with degradation by ZnO₂ and TiO₂. Pseudo first order kinetics was followed by degradation of pharmaceutical wastewater, the reaction rate constant was 0.00148/min for TiO₂/H₂O₂. It is evident by the study that actual pharmaceutical wastewater reacts in a different way to the catalyst as compare to synthetic pharmaceutical wastewater.