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Anatomical and biochemical alterations in foliar galls of Alstonia scholaris (L.) R. Br. induced by the insect Pauropsylla tuberculata (Psyllidae) are described and quantified in this study. Galls may occur, isolated or agglomerated on both surface of the leaf. The insect along with the egg deposits some physiologic fluid which acted as a stimulant for the induction of the gall. These galls caused changes in morphology and physiology which involved in biochemical changes. There was a decrease in level of chlorophyll in galls which in turn decreased photosynthetic area. Chlorophyll a and b decreased as galls progressed. Newly developed immature galls showed increase in protein contents up to two folds than healthy tissues. High proline contents were observed in mature galls than immature galls showing stressed condition of galled tissues. As disease progressed, remarkable increase in catalase activity was observed indicating response of plants defence mechanism. Steady increase in phenol contents was observed as disease progressed from immature to mature galls.