Tomato (Lycopersicon esculentum Mill) is an important fruit crop in Balochistan but its production is decreasing due to severe attack of Curly top virus (CTV). In this study, eight commercial tomato genotypes were evaluated against CTV and four varieties Dormin, Lema, Yaaqi, and Xico expressed 8–10.5% infection. The Dollar showed 11% infection whereas a high level of infection of 20–25% was recorded in local and Roma, respectively. Severa was highly resistant, Dormin, Lema, Yaqi, and Xico were resistant, Dollar was susceptible and Roma and Local were highly susceptible against CTV. The maximum biological yield was recorded in Severa followed by Dormin and Lema while lower biological yield was recorded in Local. Severa was found resistant with maximum yield and further suggested for the cultivation in Balochistan.