Biodiesel which comes from pure renewable resources provide an alternative fuel option for future because of limited fossil fuel resources as well as environmental concerns. The transesterification of vegetable oils for biodiesel production is a promising process to overcome these future crises of  energy. Biodiesel is a promising alternative fuel for future. As its production is increasing, the production of the principle co-product crude glycerol is also increasing. Currently the large surplus of glycerol formed as a by-product during the production of biodiesel offered an abundant and low cost feedstock. The optimization of biodiesel process and the effective utilization of crude glycerol can contribute to the viability of biodiesel. Researchers showed a surge of interest in using glycerol as renewable feedstock to produce functional valuable chemicals. The present work focuses on biodiesel production from palm oil and recent developments in the conversion of glycerol into value-added products especially polyglycerol (diglycerol, triglycerol and tetraglycerol). The etherification of glycerol over alkaline catalyst was done under microwave irradiation instead of conventional way. The effect of microwave irradiation on the conversion of glycerol was observed. It was found that maximum 98% glycerol converted within 60 minutes under microwaves in the presence of alkaline catalyst while maximum conversion 87 % into polyglycerol with in 3 hour of reaction into microwave reactor. This versatile new applications of glycerol in the everyday life and chemical industry will improve the economic viability of the biodiesel industry.