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Central Asia which is referred as the Heart of Asia, geopolitically, geographically, strategically, economically, politically, militarily as well as from cultural aspirations consequential and appreciable from the arteries of Pakistan and India. Pakistan being the agricultural and industrially thriving and proliferate state agog and inquisitive in securing its correspondence with Central Asian Republics. Besides this, India’s most favorable interests being a part of this Afghan closest border territory for the attainment of more liberalized Indian market in terms of trade, sea-routes, by-road links and marketing simultaneously also for the purpose of becoming richest one in the natural resources from this main hub and pivot of Asia. In this article, both Pakistan and India are described as the beady-eye for each other that which of either global opposite authority would rise up in gambling the reserves or making more obliging and amenable connections within this region irrespective to different problems and obstacles. Both these resistant states i.e. Pakistan and India, either for one or the other reasons such as for the objective of energy resources, for the military services, for regional as well as for global meshing or coalescing continuously modeling and assembling themselves knotting with this earth surrounded land. In the economic subject, Central Asian Republics act as a donor and donee in the international circle. The contribution of organizations especially that of Shanghai Corporation is essential part in which not only Pakistan and India involved but also Russia, China and USA as reverberation actors in trading and trafficking inter-state Central Asian Republic.