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South Asia is an important but complex region. Its manifold complexity is largely ascribed through historical, economic, political and strategic manifestations. The region has witnessed instability in all the given premises and interactions. The entirety happens to be the fact that the structure of alignments is motivated by security complexes which involve cohesion of foreign powers and regional states. The US, Russia, Iran and China now make out to be contemporary stakeholders in South Asian security equation. Their involvement has been seen as a major reorientation in the regional dynamics in terms of political, economic and security characteristics. The manifold possibilities of re-alignments are what the future of the region will look like. The chance of full-fledged strategic alliance in the face of US-India on the basis of similar political, economic and security interests is on the horizon. As a corollary to this alliance pattern, there is China-Russia-Pakistan alliance which is similar in force but opposite in direction. These two systems are one set of opposition forces to each other, which are also natural in form. Another structure which occurs out of the regional dynamics happens to be of India-Iran-Afghanistan which is a trifecta aiming at Pakistan. On the other hand, Russia-China-Pakistan which could turn into a politically motivated and economically driven alliance and can also cover certain aspects of security. Therefore, due to various changes in order there will stem out various patterns of relationships, which could set the order of the region as one marked by various fluctuating alignment patterns.