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In vitro herbicidal potential of Azadirachta indica A. Juss. leaf extracts @ 2, 4, 6, 8 and 10 g 100 mL^-1 was evaluated against Achyranthes aspera L. and Senna occidentalis L. Data revealed that all the concentrations inhibited seed germination and root, shoot growth with the most marked inhibition being achieved by the 10 g 100 mL^-1  concentration. Germination was suppressed by 7-59% in case of A. aspera and by 3-41% in S. occidentalis. Shoot length was reduced by 2-12 mm and by 3-12 mm where as root length was declined by 5-23 mm and 2-11 mm for A. aspera and S .occidentalis, respectively. The herbicidal effect of the extracts against the test weeds seemed to be directly proportional with concentrations.